Preparation of alginate coated chitosan microparticles for vaccine delivery
نویسندگان
چکیده
منابع مشابه
Preparation of alginate coated chitosan microparticles for vaccine delivery
BACKGROUND Absorption of antigens onto chitosan microparticles via electrostatic interaction is a common and relatively mild process suitable for mucosal vaccine. In order to increase the stability of antigens and prevent an immediate desorption of antigens from chitosan carriers in gastrointestinal tract, coating onto BSA loaded chitosan microparticles with sodium alginate was performed by lay...
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Recently, efforts have been focused on microparticles prepared with natural polymers such as alginates and chitosans. Sodium alginate in particular has been commercially applied and investigated due to its low cost and minimal processing requirements (Murata et al., 1993; Gombotz & Wee, 1998; Sezer & Akbuga, 1999a and b). The use of sodium alginate for microencapsulation has been extensively st...
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ژورنال
عنوان ژورنال: BMC Biotechnology
سال: 2008
ISSN: 1472-6750
DOI: 10.1186/1472-6750-8-89